CORDIS Project
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The TAU-NOW project investigates the mechanisms of tau pathology in Alzheimer's disease, focusing on how tau spreads in the brain and identifying factors that contribute to resilience against this condition. It employs advanced imaging techniques and cognitive assessments to enhance understanding of Alzheimer's progres…
Alzheimer’s disease (AD) poses a major challenge, as 40 million people worldwide are diagnosed with AD and there is currently no cure. AD is characterized by Aβ plaques and tau neurofibrillary tangles.
Recently, several phase III clinical trials targeting the Aβ pathway have failed to reach their primary endpoints.
This stresses the need for diversification of the drug portfolio.
Tau pathology is a promising drug target due to its strong associations with synaptic density, atrophy and cognition.…
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Netherlands, Amsterdam
Type: Research institute
Activity type: Research Organisations
SME: No
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