CORDIS Project
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This project aims to enhance influenza vaccine effectiveness by profiling T cell responses at a single-cell level. It investigates the role of T cell subpopulations in immune protection against flu, focusing on how different adjuvants influence these responses to improve vaccine design.
Mutating viruses and resistance to drugs are the major challenges to overcome in influenza (flu) prevention and treatment.
Virus-neutralizing antibodies are the key for protection against flu infection, but flu-specific CD4+ and CD8+ T cells play a significant role by providing help to B cells and in viral clearance, respectively.There are many vaccines against flu infection approved for human use.
The generally effective seasonal vaccines, however, have a number of deficiencies, including the n…
GLAXOSMITHKLINE VACCINES SRL
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