CORDIS Project
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This project investigates the characteristics and functions of B lymphocytes in teleost fish, specifically rainbow trout, challenging the assumption that they function like mammalian B2 lymphocytes. It aims to explore their unique antibody responses and potential implications for vaccination strategies and understandin…
Teleost fish are the most primitive bony vertebrates that contain immunoglobulins, although belonging to different classes than those of mammals, having only IgM, IgD and IgT.
No Ig maturation to more specific class is observed in fish, providing them with an antibody response that is slow and weak in terms of antigen affinity.
This is the main reason why protection conferred by disease natural resistance or vaccination does not correlate with an antibody response.
Despite these great difference…
INSTITUTO NACIONAL DE INVESTIGACION Y TECNOLOGIA AGRARIA Y ALIMENTARIA
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