CORDIS Project
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This project aims to identify and validate biomarkers related to telomere dysfunction in cancer. By studying the telosome complex, it seeks to improve early diagnosis and treatment of cancer through novel molecular targets.
Telomeres are DNA-nucleoprotein structures that protect the ends of human chromosomes through the formation of a ‘cap’ that prevents exonucleolytic degradation, inter- & intra-chromosomal fusion and subsequent chromosomal instability.
Telomerase, the ribonucleoprotein enzyme that maintains linear chromosomal DNA ends by the addition of TTAGGG repeats, is completely repressed or present only at low, tightly regulated levels in normal human cells as a safeguard against cancer.
Normally, telomere s…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
United Kingdom, Glasgow
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Switzerland, Lausanne
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Germany, Freiburg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Sweden, Umea
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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