CORDIS Project
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This project investigates how mechanical tension influences the growth and remodeling of epithelial tissues. By exploring competing mechanisms like fluidization versus reinforcement and cell division versus apoptosis, it aims to understand how local cellular processes contribute to global tension patterns in tissue org…
Throughout development and adult life, the growth and remodelling of living tissues is determined by a complex interplay between chemical and physical cues.
Among such physical cues, mechanical tension is emerging as central regulator of cellular fate and function.
To explain tension regulation, current research emphasizes molecular mechanisms at an ever increasing level of detail.
How these local mechanisms are integrated to give rise to global patterns of tissue tension is unknown, however.
Th…
FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
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