CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates the mechanisms of RNA-directed DNA elimination in Tetrahymena, focusing on how small RNAs influence mating type determination. It aims to uncover the roles of specific proteins in this process and their connections to chromatin functions.
Tetrahymena eliminates micronuclear-limited sequences from the developing macronucleus during sexual reproduction (DNA elimination).
It is believed that the DNA to be eliminated is identified by their homology with ~28 nt small RNAs (scnRNAs) which are made by a RNAi-related mechanism.
Detailed mechanisms as well as exact biological functions of the RNA-directed DNA elimination remain obscure.
The goal of this specific project is to understand: (i) How a RNAi-related mechanism directs DNA elimin…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
