CORDIS Project
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This project investigates how the genetic instructions of an organism are translated into its cellular functions by examining the role of transcription factors and chromatin structure. By manipulating chromatin in living cells, it aims to understand the relationship between chromatin modifications and gene regulation.
How the genomic blueprint of an organism is translated into cellular phenotype is a fundamental question in modern biology.
The instructions need to be specifically regulated for cells to function.
The regulation of the readout of this information is not entirely written in the DNA sequence but also requires epigenetic directives like DNA and histone modifications.The maintenance of cellular states as well as their controlled differentiation requires the establishment of correct transcriptional…
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
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