CORDIS Project
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This research investigates how allergic asthma affects the development of dendritic cells, which play a crucial role in immune responses. It aims to identify the mechanisms influencing dendritic cell differentiation in the context of allergen exposure.
Allergic asthma is a chronic inflammatory disease of the airways and a worldwide problem.
Dendritic cells (DC) have a key role in the development of this disease, making them interesting targets for therapy.
Novel asthma therapies could involve interference with the development and relative abundance of functionally specialized lung DC subsets.
Allergen exposure drastically changes airway DC subset distribution and preliminary experiments show effects on myeloid bone marrow progenitors.
We hypot…
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