CORDIS Project
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This project investigates the nanomechanical mechanisms of fusion pore formation during exocytosis, focusing on the role of SNARE proteins. By employing advanced microscopy and electrochemical detection, it aims to elucidate the molecular dynamics involved in cellular and viral fusion processes, with potential implicat…
Cells release neurotransmitters, hormones and other compounds stored in secretory vesicles by a process called exocytosis.
In this process, the molecules are released upon stimulation by a nanomachine forming a fusion pore that connects the vesicular lumen to the extracellular space.
Similar fusion events are also essential for intracellular transport mechanisms and virus-induced fusion.Here I propose a multidisciplinary approach using highly innovative techniques to determine the nanomechanical…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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