CORDIS Project
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This project explores the role of cardiac progenitor cells in heart regeneration after myocardial infarction. It examines how beta-adrenergic signaling influences these cells' activation and function, aiming to identify therapeutic targets to reduce cardiac damage and improve recovery following heart attacks.
Cardiovascular diseases are a leading cause of mortality in the industrialized world with myocardial infarction (MI) being one of the common pathological events.
Cardiac progenitor cells (CPC) are a progenitor cell population within the myocardium and are activated after MI to proliferate, migrate to the infarct site, and participate in cardiac regeneration. CPC are a current therapeutic target to diminish cardiac injury after a MI.
After a MI, the beta-adrenergic system gets activated due to ex…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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