CORDIS Project
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This project investigates how receptor signal transduction occurs within cells, focusing on the roles of RIN3 and ACAP1 in membrane trafficking and immune cell function. By studying genetically modified mice, the research aims to uncover the mechanisms of signal compartmentalization and its implications for immune diso…
Recently, receptor signal transduction has been identified to occur not only at the plasma membrane, but also at various intracellular compartments.
Hence, receptor trafficking and signal compartmentalization may contribute to a higher level of cellular organization.
The proposal’s objective is to understand fundamental principals in the regulation and biology of membrane trafficking and signal compartmentalization, and to test them in a physiological context.
The overall research concept is to…
FORSCHUNGSZENTRUM BORSTEL LEIBNIZ LUNGENZENTRUM
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