CORDIS Project
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This project examines the impact of microRNAs on bipolar cells in the retina, building on previous findings about their role in cone photoreceptors. It aims to identify specific microRNA and messenger RNA interactions that regulate synaptic transmission and contribute to visual processing.
Studies conducted at the Friedrich Meischer Institute (FMI) in Basel have focused on the roles of miRNAs specific to the retina.
They have recently shown that absence of functional miRNA expression has severe consequences on mature cone photoreceptors of the mouse retina; a selective and dramatic reduction of cone-specific gene expression arises with the cone-specific loss of regulation by miRNAs in adult mice.
The bipolar cells act post-synaptically to the photoreceptors where they not only tra…
FRIEDRICH MIESCHER INSTITUTE FOR BIOMEDICAL RESEARCH FONDATION
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