CORDIS Project
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This project focuses on understanding immune responses to tick bites, particularly the roles of specific immune cells and sensory neurons. By studying these interactions, the project aims to enhance knowledge of how to combat diseases transmitted by ticks.
Ticks are ectoparasites and major vectors of human and animal pathogens.
Vector-borne diseases are an increasing threat in Europe, yet the molecular immunology of host responses to tick bites remains poorly understood.
Tick saliva suppresses immunity, and although type 2 granulocytes such as mast cells, basophils, and eosinophils are recruited and activated at the bite site, their role in anti-tick immunity is unclear.
Similarly, sensory neurons are emerging as important regulators of skin immun…
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