CORDIS Project
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This project aims to identify and validate therapeutic targets for pancreatic and lung cancers driven by K-RAS mutations. It focuses on understanding the genes involved in tumor initiation and developing combination therapies to improve treatment outcomes.
This proposal is aimed at identifying and functionally validating targets with potential therapeutic value to devise novel strategies to treat two human cancers with unacceptable low survival rates and unmet medical needs: pancreatic ductal adenocarcinoma and K-RAS mutant lung adenocarcinoma.
Although these tumor types have distinct pathological and clinical manifestations, they are both driven by K-RAS mutations.
Hence, we expect that the proposed studies will generate synergies to accelerate t…
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