CORDIS Project
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This research focuses on understanding how hypothalamic neurons detect temperature, which is crucial for maintaining body temperature. By studying the role of specific ion channels in these neurons, the project aims to uncover mechanisms that could lead to new treatments for pain and inflammatory conditions.
Internal temperature homeostasis is of critical importance to our health as deviation from a normal, tightly controlled level (37 °Celsius) can cause fatal organ failures.
Temperature-sensitive cells in the hypothalamus detect deep brain temperature, which is directly relevant to core body temperature (CBT) regulation.
However molecules and mechanisms underlying central temperature detection by hypothalamic neurons are unknown. I propose to use a multi-disciplinary approach to elucidate mechanis…
UNIVERSITATSKLINIKUM HEIDELBERG
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