CORDIS Project
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This project investigates the molecular mechanisms behind the plasticity of T helper cells, focusing on the transition from Th2 to Th1 cells. By employing experimental and computational methods, it aims to uncover gene expression dynamics and epigenetic changes, which are crucial for developing targeted therapies for a…
Naïve CD4+ T cell differentiate into distinct lineages to achieve successful adaptive immune responses to diverse categories of pathogens.
The development of these effector cells is controlled by cytokines, transcription factor interactions and chromatin modifications.
In addition, several of the differentiated subtypes can interconvert, a property known as plasticity.
However, the molecular regulation of flexibility of this subset cells is still unresolved. I propose to explore the molecular m…
GENOME RESEARCH LIMITED
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United Kingdom, LONDON
Type: Public body
Activity type: Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments)
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