CORDIS Project
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TIRCON addresses the urgent need for therapies in neurodegenerative disorders characterized by brain iron accumulation, particularly pantothenate kinase-associated neurodegeneration (PKAN). The project aims to conduct a clinical trial for a drug treatment and develop a patient registry to facilitate future research.
Neurodegeneration with brain iron accumulation (NBIA) is a heterogeneous group of rare hereditary neurodegenerative disorders characterized by high levels of brain iron.
The most common form is pantothenate kinase-associated neurodegeneration (PKAN).
Classic PKAN and most other NBIA cases are characterised by early childhood onset and rapid progression.
Currently, there is no proven therapy to halt or reverse PKAN or any other NBIA.
This is especially unfortunate as both the iron accumulation in…
LUDWIG-MAXIMILIANS-UNIVERSITAET MUENCHEN
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Germany, Muenchen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
INSTYTUT POMNIK CENTRUM ZDROWIA DZIECKA
Poland, Warszawa
Type: Research institute
Activity type: Research Organisations
SME: No
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
Netherlands, Groningen
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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