CORDIS Project
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This project aims to develop new tools for selectively depleting tissue-resident regulatory T cells to study their specific functions in various organs. By creating a targeted approach, it seeks to enhance understanding of immune responses and tissue-specific roles of these cells.
Regulatory T cells (Tregs) are formed through the expression of the transcription factor Foxp3 in T cells, resulting in the rewiring of the cell function into an immunosuppressive phenotype.
Recently, it has been proposed that Tregs also have additional tissue-specific physiological roles when resident in different tissues.
For example, tissue-specific Tregs residing in the muscle and adipose tissue possess immunological and non-immunological functions in these tissues, distinct from the generic…
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VLAAMS INSTITUUT BIOTECHNOLOGIE FLANDERS INSTITUTE FOR BIOTECHNOLOGY
Belgium, ZWIJNAARDE - GENT
Type: Research institute
Activity type: Research Organisations
SME: No
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