CORDIS Project
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This project aims to develop new treatments for Hepatitis C Virus infection by understanding the relationship between the virus and host lipid metabolism. It focuses on creating microfabricated platforms for high-throughput screening of potential drug combinations to minimize viral replication.
Hepatitis C Virus (HCV) infection affects over 3% of the world population and is the leading cause of chronic liver disease worldwide.
Current treatments are effective in only 50% of the cases and associated with significant side effects.
Therefore, there is a pressing need for the development of alternative treatments.
Recently, our group and others demonstrated that the HCV lifecycle is critically dependent on host lipid metabolism.
In this context, we demonstrated that the grapefruit flavonoi…
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