CORDIS Project
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This project investigates the role of nucleic acid-sensing Toll-like receptors in cancer, focusing on their dual effects on tumor cells and the immune response. By analyzing tumor-associated cells, it aims to uncover mechanisms that could enhance immunotherapy effectiveness.
Inflammation is an integral part of carcinogenesis.
Several different cells of myeloid, lymphoid and non-hematopoietic origin contribute to the strong link between cancer and inflammation and maintain a pro-tumoral environment.
The complexity of this environment and the diversity of tumours lead to distinct responses during tumour immunotherapies.
Nucleic acid-sensing (NAS) TLR ligands are an essential component of anti-tumour strategies to induce efficient tumour-specific adaptive immune respon…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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