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The TOMAC project introduces a new flow system called Magnetic Artificial Cilia for Organ-on-a-Chip devices, enhancing drug testing by mimicking human tissue responses more accurately. This technology aims to improve the reliability of preclinical drug testing without relying on animal models.
Currently, 90% of the drugs fail to pass clinical trials1.
One of the key reasons is that the animal models used in the preclinical phase poorly predict the human response to the drugs.
Organ-on-a-Chip (OoC) is a game changing technology as one of the alternative methodolgies to animal models.
The heart of an OoC system is an ‘Organ-chip’: cm-sized devices with micro-channels and -chambers in which human cells can be grown to closely mimic human tissues.
More and more evidence shows that OoCs ar…
TECHNISCHE UNIVERSITEIT EINDHOVEN
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