CORDIS Project
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The TOPIC project focuses on targeting toxic protein aggregates linked to Parkinson's and Huntington's diseases. It trains researchers to use advanced techniques to identify and quantify these harmful oligomers, aiming to develop small-molecule inhibitors that could halt disease progression and cell death.
Parkinson's disease and Huntington's disease are highly debilitating diseases for which no disease modifying treatment is available.
This EID proposal, called TOPIC (Targeting Cytotoxic Protein Oligomers), will train 2 ESRs to target the oligomeric protein aggregate which accumulates in these diseases.
These oligomers occur under conditions which eventually lead to the accumulation of fibrillar amyloid deposits.
However, there is increasing consensus that the amyloid state is biologically inert…
AARHUS UNIVERSITET
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Netherlands, UTRECHT
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
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Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
