CORDIS Project
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This project investigates synaptic plasticity in cortical microcircuits, specifically focusing on layer 5 pyramidal cells. It aims to characterize the plasticity rules among different neuron types using advanced imaging and electrophysiological techniques.
The cortex has been described to display synaptic plasticity, which is determinant for the function of cortical microcircuits.
Although there is a large literature on neocortical plasticity, most of the experiments addressed the connections of pyramidal cells located in particular cortical layers, so the majority of intracortical connections are yet unexplored with respect to their plasticity.
Moreover, these studies are contradictory in that apparently synaptic plasticity rules like spike-timin…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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