CORDIS Project
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This project investigates how chromatin is reprogrammed to totipotency in mammalian zygotes, focusing on the mechanisms and spatial organization involved. By combining cell biology, genetics, and genomics, it aims to uncover key regulators that facilitate this critical developmental stage, which is essential for unders…
Totipotency, the developmental potential of a cell to give rise to all cell types, is naturally achieved when differentiated egg and sperm fuse to form the one-cell zygote.
How chromatin is epigenetically reprogrammed to totipotency within hours after fertilisation remains a central question in biology.
We aim to address this by investigating the mechanisms of reprogramming and the spatial reorganisation of chromatin in mammalian zygotes.
Our interdisciplinary approach combines mechanistic cell…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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Austria, Wien
Type: Company (for-profit)
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: No
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