CORDIS Project
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This project investigates the mechanisms behind the encystation of Toxoplasma gondii, a parasite that infects warm-blooded animals. It focuses on understanding cyst wall formation and the parasite's adaptation to host immune responses, utilizing advanced technologies to uncover potential intervention targets.
Toxoplasma gondii is the most successful obligate intracellular parasites infecting virtually all warm-blooded animals. A infection initiates with the dissemination of the fast-replicating tachyzoites.
At the onset of the immune response tachyzoites convert into slow-growing bradyzoites that form cysts in the central nervous system and in striated and heart muscles.
Encystation ensures life-long persistence and poses a significant threat of reactivation during immunosuppression and can lead to e…
UNIVERSITE DE GENEVE
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