CORDIS Project
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This project investigates the role of CD8+ T cells in controlling viral infections, particularly focusing on non-killer resident memory T cells. By utilizing advanced single-cell technologies, the research aims to map T cell distribution and function across different tissues, with implications for understanding immune…
The current Covid-19 pandemic highlights the need to gain better understanding of precise mechanisms that enable immune control of viral infections.
Although it is established that CD8+ T cells are required to suppress viremia, most view these cells simply as ?killer T cells? based almost exclusively on studies of blood. I recently discovered that efficient immune control of HIV is mediated primarily by non-killer resident memory CD8+ T cells, whereas CD8+ T cells with high ?killer instinct? are…
KAROLINSKA INSTITUTET
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