CORDIS Project
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The TRANS-3 project aims to explore the structure and function of inter-chromosomal genome interactions, focusing on how mRNA factories influence gene regulation. By studying a specific splicing factory involving multiple chromosomes, the project seeks to uncover the mechanisms behind chromatin domain formation and the…
In TRANS-3 we will develop the theoretical and experimental framework to understand inter-chromosomal genome structure and activity.
Despite advances in sequencing chromosomes and mapping their three dimensional (3D) organization, a full picture of 3D genome structure that details how the borders of various chromosome territories functionally interface one another is still missing.
As an analogy, our world map does not indicate most natural corridors or manmade infrastructure that connect countr…
UNIVERSITA DEGLI STUDI DI TORINO
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