CORDIS Project
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This project aims to develop brain organoid models for schizophrenia, bipolar disorder, and major depressive disorder by targeting specific transcription factors. By utilizing advanced genomic technologies, the research seeks to identify key regulatory molecules that contribute to these psychiatric disorders, improving…
Schizophrenia (SCZ), bipolar disorder (BP), and Major Depressive Disorder (MD) are three major psychiatric disorders that affect mood, thinking, and behavior.
These disorders are strongly genetically intercorrelated, and exhibit pronounced clinical overlap, suggesting that they are different manifestations of a shared underlying neurobiology, along a spectrum.
However, the neurobiological mechanisms and pathophysiology of these disorders are still poorly understood, limiting effective drug disco…
UNIVERSITAIR MEDISCH CENTRUM GRONINGEN
ACADEMISCH ZIEKENHUIS GRONINGEN
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