CORDIS Project
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This project investigates the phenomenon of length dependence in transposons, which limits their effectiveness in gene delivery applications. By developing biochemical and genetic assays, the research aims to identify the causes of this limitation and explore transposons that may be free from length dependence, ultimat…
Transposons are important tools in genetics and molecular biology.
They are widely used in academic and industrial settings where technical innovations continually expand the range of applications.
Transposons are promising tools in synthetic biology and gene therapy applications.
The amount of DNA a transposon can carry is in principal unlimited.
However, in practice, when transposon length is increased, for example by the addition of a therapeutic transgene, its ability to transpose is reduced…
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