CORDIS Project
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This project investigates the role of tandem repeats in the genetic basis of neurodegenerative diseases. By analyzing neuronal DNA instability and its effects on degeneration, the research aims to identify potential targets for prevention and treatment of these conditions.
Dementia and other neurodegenerative diseases are among the leading causes of disability worldwide and have an immense societal impact due to lack of effective treatments.
For developing better preventive and therapeutic strategies, it is essential to clarify their still largely elusive genetic basis and pathophysiology.
Emerging insights from the study of rare hereditary repeat expansion disorders caused by elongations of repetitive DNA sequences (""tandem repeats"" (TRs)) indicate that TRs cou…
DEUTSCHES ZENTRUM FUR NEURODEGENERATIVE ERKRANKUNGEN EV
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