CORDIS Project
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This research focuses on the role of the TOR kinase in regulating protein synthesis in plants. It aims to uncover how environmental signals are integrated to control translation initiation, particularly in stem cell tissues.
Translation is a critical step in the regulation of gene expression in eukaryotes.
Most of the control occurs at the level of translation initiation, which is a rate-limiting step in protein synthesis.
In mammals, cap-dependent translation initiation is under the regulation of the target of rapamycin (TOR) protein kinase, which suppresses the function of translation repressor proteins, the eIF4E-binding proteins (4E-BPs) that sequester the cap-binding factor eIF4E at the 5′-end of mRNA.
The TOR…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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