CORDIS Project
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This project investigates transposable elements in the human genome, which play significant roles in gene regulation and evolution. It aims to uncover their mechanisms and implications for human development and disease, with potential applications in research and medicine.
Transposable elements (TEs) account for more than two thirds of the human genome.
They can inactivategenes, provide novel coding functions, sprinkle chromosomes with recombination-prone repetitivesequences, and modulate cellular gene expression through a wide variety of transcriptional andposttranscriptional influences.
As a consequence, TEs are considered as essential motors of evolution yetthey are occasionally associated with disease, causing about one hundred Mendelian disorders and possibly…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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