CORDIS Project
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This project investigates structural differences in ribosomes between protozoa and mammals to enhance understanding of protein synthesis regulation. The research aims to identify potential drug targets for treating diseases caused by eukaryotic pathogens.
mRNA translation consists on translating the genetic code to proteins by the ribosome that is universally conserved in all cells.
However, its structure presents significant differences between bacteria and eukaryotes.
Partly because of these differences, the bacterial ribosome can be targeted specifically by a number of antibiotics without affecting the eukaryotic host cells.
However, the conservation of the ribosome among eukaryotes complicates the search for specific drugs against eukaryotic…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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