CORDIS Project
Funding breakdown and partner intelligence are Premium
Sign in and upgrade to Premium for EU contribution totals, consortium analytics, OpenAlex research context, and AI summaries. · 0 consortium intelligence fields visible of 1
Start free • Cancel anytime • 14-day refund guarantee
This project investigates how antibodies against transglutaminase 2 affect blood vessel function in celiac disease. By studying these interactions in various models, the research aims to identify potential therapeutic targets to improve vascular health in affected patients.
Celiac disease (CD) is a common heritable autoimmune disorder triggered by gluten-containing cereals which induce a massive immune reaction and destruction of the small bowel mucosa.
The disease is hallmarked by the production of antibodies against transglutaminase 2 (TG2), an enzyme involved in angiogenesis.
Interestingly CD presents an entire disorganization of the intestinal vasculature where the TG2 autoantibodies are deposited.
We recently demonstrated that anti-TG2 antibodies can disrupt a…
TAMPEREEN YLIOPISTO
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Similar projects, consortium collaboration history, frequent partners, and OpenAlex research context.
Guests see up to 5 EuroSciVoc fields.
Guests see up to 5 topics.
