CORDIS Project
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This project aims to convert human fibroblasts into dopamine neurons, which are crucial for understanding and treating Parkinson's Disease. By developing patient-specific neurons, it seeks to advance research on disease mechanisms and potential therapies.
Cellular reprogramming is a new and rapidly emerging field where somatic cells can be turned into pluripotent stem cells or other somatic cell types simply by overexpression of specific combinations of genes.
This remarkable discovery allows for the generation of patient specific cell lines that will serve as major tools for understanding how diseases arise and develop, and they may also prove useful for drug screens, diagnostics and other biomedical applications.
We have developed a reprogrammi…
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