CORDIS Project
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This interdisciplinary project explores the role of immune responses in Alzheimer's disease by studying Aβ-specific regulatory T cells. It aims to understand how these cells can regulate inflammation and promote the clearance of harmful proteins in the brain, paving the way for safer therapies.
With populations ageing, Alzheimer’s disease (AD), for which there is still no cure, has become a major public health problem in Europe.
This is partly due to the neglect of the role of the immune responses to the build-up of cerebral Aβ-the pathogenic agent triggering AD.
Clinical trials for vaccines aimed at reducing cerebral Aβ were accompanied by severe side effects due to improper neuroinflammation.
While the input of microglia, the brain resident innate immune sentinels, is becoming clear…
THE PROVOST, FELLOWS, FOUNDATION SCHOLARS & THE OTHER MEMBERS OF BOARD, OF THE COLLEGE OF THE HOLY & UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN
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