CORDIS Project
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This project investigates the evolutionary origins of terpenes in plants, focusing on the enzymes responsible for their production. By examining structural changes in these enzymes, the research aims to enhance our understanding of triterpene complexity and facilitate the engineering of novel compounds.
Plants have evolved the ability to produce diverse terpenes to communicate, thrive and survive in various ecologies and these have profound benefits for humanity as therapeutics and bioactive compounds.
While chemical novelty has contributed to the success of sessile organisms like plants, the evolutionary origins of terepene complexity are poorly understood at the molecular level.
Among terpenes, triterpenes are produced by oxidosqualene cyclase (OSC’s) family members.
In OSC family, beta-amyri…
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