CORDIS Project
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The project investigates the dynamics of fungal fatty acid synthase, a complex involved in fatty acid production. By combining structural biology and molecular dynamics simulations, it aims to understand the transport and regulation of fatty acid synthesis, which is crucial for developing biofuels and fine chemicals.
Fatty acids are essential metabolites used in biological cell wall formation, energy storage, and signal transduction.
Fatty acid synthesis is carried out in an iterative sequence of reactions, conserved across all species.
Yet different organisms have developed different solutions, the most impressive is the fungal fatty acid synthase (FAS).
The 2.6 MDa molecular complex integrates all enzymatic functions required for the stepwise assembly of fatty acids.
Its architecture is reminiscent of a ch…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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