CORDIS Project
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This project focuses on commercializing a new T-cell therapy for acute lymphoblastic leukemia using genetically modified T-cells that target a specific cancer enzyme. Preclinical studies show promising results in eradicating cancer cells while sparing healthy cells.
The aim of this PoC project is to commercialize new therapy for acute lymphoblastic leukemia (ALL) developed in context of my ERC consolidator grant. T-cell receptors (TCRs) have in recent years emerged as promising therapeutic molecules in cell- and gene-therapy of cancer. I have completed the pre-clinical validation of a TCR that recognizes an HLA-bound peptide from a novel target, the nuclear enzyme terminal deoxynucleotidyl transferase (TdT-TCR).
In vitro and in vivo data from four different…
OSLO UNIVERSITETSSYKEHUS HF
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Norway, Eiksmarka
Type: SME
Activity type: Private for-profit entities (excluding Higher or Secondary Education Establishments)
SME: Yes
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