CORDIS Project
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This project combines optical trapping and tip-enhanced Raman spectroscopy to study the mechanical and chemical properties of supramolecular systems at the single-molecule level. It aims to understand the interactions governing molecular motors and enhance techniques in single-molecule manipulation.
Quantitative information on the dynamics and mechanistic principles behind supramolecular systems can be investigated in the single-molecule regime by measuring the nanometer displacements resulting from the application of picoNewton forces in optical trapping (OT) experiments.
In particular, the mechanical strength of non-covalent interactions can be quantified when studying the reversible breaking/formation of hydrogen bonds on individual host-guest systems or the switching of a macrocycle bet…
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