CORDIS Project
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This research explores how ageing affects the immune response, particularly in relation to vaccine efficacy. It aims to identify the cellular mechanisms behind the decline in immune function with age, focusing on specific T cell populations and the impact of senescent cells.
A major accomplishment of modern society is the extension of human life expectancy.
However, this creates a new challenge for medical science, to facilitate healthy ageing.
With age, the function of the immune system declines, rendering older people more susceptible to infections and less able to benefit from vaccination.
Indeed, improving vaccine efficacy is key to reducing infection-related morbidity in older people.
To date, the complexity of the ageing process has hindered attempts to fulf…
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