CORDIS Project
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U-BIOPRED focuses on improving drug development for severe asthma by creating detailed biomarker profiles. These profiles will help identify sub-phenotypes of asthma and enhance the predictability of therapeutic outcomes through a systems biology approach.
RationaleThe inability of pre-clinical studies to predict clinical efficacy is a major bottleneck in drug development.
In severe asthma this bottleneck results from: a lack of useful and validated biomarkers, underperforming pre-clinical models, inadequate and incomplete sub-phenotyping, and insufficient disease understanding.HypothesisThe use of biomarker profiles comprised of various types of high-dimensional data, integrated with an innovative systems biology approach into distinct phenotype…
NOVARTIS PHARMA AG
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
Netherlands, Amsterdam
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, Southampton
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE
United Kingdom, LONDON
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
Italy, Catania
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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