CORDIS Project
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This project focuses on synthesizing disorazole C1 analogues, natural products with strong anticancer properties. By employing advanced synthesis techniques and structural analysis, the project aims to better understand their mechanism of action against cancer cells, including those resistant to multiple drugs.
Cancer is a common and life-threatening disease with world-wide occurrence, and the number of affected individuals and morbidity continues to increase annually.
It is therefore of great importance that straightforward syntheses of potential anti-cancer agents are developed in order to advance treatment and drug discovery in this field.
The disorazoles, the subject of this proposal, are a group of natural products which display strong anticancer activity against a variety of cell lines, including…
THE UNIVERSITY OF EDINBURGH
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