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The uF-NMR project develops microfluidic devices for live cell culture and metabolome analysis using nuclear magnetic resonance spectroscopy. This innovative approach allows for real-time characterization of cellular processes without the need for sample extraction.
uF-NMR aims at the development of microfluidic devices that allow the culture and manipulation of populations of live cells while characterising their metabolome in situ through NMR spectroscopy.
The basic paradigm is the direct interrogation of sample volumes on the chip.
This is achieved through integrating micro-fabricated radio frequency resonators into the microfluidic device.
Rather than extracting aliquots for analysis, the entire chip is inserted into a specially designed NMR probe for t…
UNIVERSITY OF SOUTHAMPTON
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