CORDIS Project
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This project investigates the role of ultraconserved elements in shaping the morphology of squamate reptiles, focusing on their influence on cranial and limb diversity. By analyzing genomic data and 3D scans of museum specimens, it aims to enhance understanding of evolutionary changes in these traits.
The genomic determinants of morphological change are of great interest to evolutionary biologists, particularly how they relate to the loss and evolution of key traits.
Ultraconserved elements (UCEs) are regions of genomes that are highly conserved across distantly related organisms.
Many UCEs are located in cis-regulatory (enhancer) regions of the genome that play critical developmental roles in determining morphology; when UCEs are removed notable changes to the skulls and limbs of mammals can…
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