CORDIS Project
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This project investigates glycosyrin, a compound secreted by the bacterium Pseudomonas syringae, which disrupts plant immunity by interfering with glycosylation processes. It aims to understand how glycosyrin manipulates plant defense mechanisms, potentially leading to new strategies for enhancing crop resistance.
The apoplast is a critical battlefield where host immunity and microbial virulence collide.
Plants rely on pattern recognition receptors (PRRs) and defense metabolites to sense and restrict microbial invasion, while pathogens evolve countermeasures to subvert these processes.
Recent studies revealed that Pseudomonas syringae secretes glycosyrin, a unique iminosugar that promotes virulence by targeting the plant-secreted β-galactosidase BGAL1. BGAL1 is required for releasing the immunogenic flg22…
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