CORDIS Project
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This project investigates human brain development using cerebral organoids to understand the specific mechanisms that drive brain expansion. It focuses on the role of spindle orientation during neural stem cell division, aiming to provide insights into human neurogenesis.
The development of the human brain is a key and fascinating question in neurobiology.
Studies in model organisms have provided enormous insight into basic mechanisms of neurogenesis, which relies on the balance between proliferation and differentiation of neural stem cells.
Although human neurogenesis follows the same principles, human specific processes that lead to human brain expansion are largely unclear.
In vitro models that recapitulate human brain development are invaluable tools to provi…
INSTITUT FUER MOLEKULARE BIOTECHNOLOGIE GMBH
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