CORDIS Project
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This project investigates the Notch signaling pathway, which is crucial for cell communication and development. By identifying new target genes, it aims to understand how Notch influences cell structure and behavior during tissue formation, with implications for developmental biology and cancer research.
Notch signalling, a cell communication pathway conserved throughout the animal kingdom, is involved in many developmental processes and linked to many diseases including cancers.
While Notch signalling is well known for its function in cell fate control, it has also been implicated in regulating cytoskeleton and cell morphology.
For example, Notch is required in Drosophila for the formation of an actin-myosin fence between dorsal and ventral compartments in the wing, for the migration of border…
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