CORDIS Project
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This research focuses on the metabolism of endothelial cells involved in blood vessel formation, aiming to understand how metabolic processes influence both normal and abnormal angiogenesis. The goal is to find ways to control tumor growth while promoting healing.
Angiogenesis is the process whereby new blood vessels are formed.
Physiological angiogenesis occurs in a variety of settings, including embryogenesis, wound healing and inflammation.
Pathological angiogenesis may occur in such settings as tumor and atherosclerotic neovascularization.
Endothelial cells exhibit remarkable plasticity and can rapidly transition to migratory and proliferative phenotypes.
This phenotypic transformation not only changes cellular physiology, but also cellular metabolic…
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