CORDIS Project
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This project explores the evolution and function of heterochromatin on the Y chromosome in Drosophila miranda. By studying transposable elements and their impact on chromatin structure, it aims to uncover fundamental mechanisms of genetic regulation.
The transition from euchromatin to heterochromatin is a fundamental process that particularly reshaped the epigenomic landscape of Y chromosome.
Its definitive genomic underpinning and broad functional impact are still unclear, as heterochromatin (e.g., that of human Y) is usually too repetitive to study. I have previously demonstrated that, the young Y (‘neo-Y’) chromosome of Drosophila miranda has just initiated such a transition, thus is a powerful model to unveil the evolution, regulation an…
UNIVERSITAT WIEN
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